images links abstract
Wiki Code Copy Tips Home

Sepsis

Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. There may also be symptoms related to a specific infection, such as a cough with pneumonia, or painful urination with a kidney infection. In the very young, old, and people with a weakened immune system, there may be no symptoms of a specific infection and the body temperature may be low or normal, rather than high. Severe sepsis is sepsis causing poor organ function or insufficient blood flow. Insufficient blood flow may be evident by low blood pressure, high blood lactate, or low urine output. Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement.

Sepsis is caused by an inflammatory immune response triggered by an infection. Most commonly, the infection is bacterial, but it may also be fungal, viral, or protozoan. Common locations for the primary infection include the lungs, brain, urinary tract, skin, and abdominal organs. Risk factors include very young age, older age, a weakened immune system from conditions such as cancer or diabetes, major trauma, or burns. An older method of diagnosis was based on meeting at least two systemic inflammatory response syndrome (SIRS) criteria due to a presumed infection. In 2016, SIRS was replaced with a shortened sequential organ failure assessment score (SOFA score) known as the quick SOFA score (qSOFA) which is two of the following three: increased breathing rate, change in level of consciousness, and low blood pressure. Blood cultures are recommended preferably before antibiotics are started, however, infection of the blood is not required for the diagnosis. Medical imaging should be used to look for the possible location of infection. Other potential causes of similar signs and symptoms include anaphylaxis, adrenal insufficiency, low blood volume, heart failure, and pulmonary embolism.

Sepsis is usually treated with intravenous fluids and antibiotics. Typically, antibiotics are given as soon as possible. Often, ongoing care is performed in an intensive care unit. If fluid replacement is not enough to maintain blood pressure, medications that raise blood pressure may be used. Mechanical ventilation and dialysis may be needed to support the function of the lungs and kidneys, respectively. To guide treatment, a central venous catheter and an arterial catheter may be placed for access to the bloodstream. Other measurements such as cardiac output and superior vena cava oxygen saturation may be used. People with sepsis need preventive measures for deep vein thrombosis, stress ulcers and pressure ulcers, unless other conditions prevent such interventions. Some might benefit from tight control of blood sugar levels with insulin. The use of corticosteroids is controversial. Drotrecogin alfa, originally marketed for severe sepsis, has not been found to be helpful, and was withdrawn from sale in 2011.

Disease severity partly determines the outcome. The risk of death from sepsis is as high as 30%, from severe sepsis as high as 50%, and from septic shock as high as 80%. The number of cases worldwide is unknown as there is little data from the developing world. Estimates suggest sepsis affects millions of people a year. In the developed world approximately 0.2 to 3 people per 1000 are affected by sepsis yearly, resulting in about a million cases per year in the United States. Rates of disease have been increasing. Sepsis is more common among males than females. The medical condition has been described since the time of Hippocrates. The terms "septicemia" and "blood poisoning" have been used in various ways and are no longer recommended.



Source: Sepsis
Journey (band)
M.S. Dhoni: The Untold Story
Syrian Civil War
SpaceX
Heath Ledger
Laurie Metcalf
George H. W. Bush
2002 FIFA World Cup
Willie Nelson
Saoirse Ronan
Shah Rukh Khan
Five Nights at Freddy's
Rana Daggubati
La7
N.W.A
Katie Holmes
Harvey Weinstein
Ludacris
Saint Lucia
Traveling Wilburys
Teen Wolf (season 6)
Martina Hingis
Steven Avery
List of TCP and UDP port numbers
Katheryn Winnick
Keegan-Michael Key
Harry Potter (film series)
James VI and I
Pompeii
Amy Adams
United States men's national soccer team
Tiffany Haddish
Jesse Plemons
All the Money in the World
Bill Gates
Pescetarianism
Albert, Prince Consort
Middle East
Anne Boleyn
59th Annual Grammy Awards
Elizabeth II
The Walt Disney Company
X-Men Origins: Wolverine
2018 FIFA World Cup qualification
Young Thug
Jimmy Garoppolo
BMW
Byzantine Empire
William H. Macy
IPad
Joseph Stalin
Anthony Rapp
Elizabeth Woodville
Chris Rock
Iron Man (2008 film)
2 Broke Girls
Dunning–Kruger effect
The Imitation Game
Anushka Sharma
Academy Awards
HTML
Southeast Asia
Nicki Minaj
The Babadook
UFC 213
Quantico (TV series)
Catherine Zeta-Jones
Greek mythology
Venus Williams
Boruto: Naruto Next Generations
Reince Priebus
Shiba Inu
Carice van Houten
Michael Schumacher
List of Harry Potter characters
Edmund Kemper
Preacher (TV series)
2016 NFL Draft
Kris Wu
Tyler, The Creator
Keerthy Suresh
Philosophy
Edward IV of England
The Strain (TV series)
Latvia
United States dollar
Christina Ricci
Magna Carta
Turkey
Stephanie McMahon
List of Hindi film clans
Chronic obstructive pulmonary disease
Moldavian Democratic Republic
Wil Wheaton
Charlie Chaplin
XXX (2002 film)
2017 NFL season
Gerald's Game (film)
Brooke Shields
Austria-Hungary
The Sopranos
Monaco
Panama Canal
Kit Harington
Donatella Versace
The World's Billionaires
To Kill a Mockingbird
Stephen Merchant
Sunny Leone
Shahid Kapoor
Joseph Fiennes
Christoph Waltz
Poppers
Jeremy Irons
2016 NBA draft
Kawhi Leonard
Johanna Konta
British royal family
Maya civilization
Adrianne Palicki
Boeing 737
Lok Sabha
Harry Dean Stanton
Sandra Bullock
Pakistan
Creed (film)
Mikhail Gorbachev
Heinrich Himmler
Pneumonia
Canary Islands
Colin Kaepernick
Martin Luther King Jr.
Beyoncé
Tiger Zinda Hai
National Basketball Association
XHamster
U2
Test data
Ukraine
Overwatch (video game)
Alabama
Huddersfield Town A.F.C.
Pirates of the Caribbean: Dead Men Tell No Tales
British Empire
Atlético Madrid
List of average human height worldwide
Tom Brady
Keira Knightley
Moana (2016 film)
Adele
Human Development Index
Battle of the Alamo
Benito Mussolini
John Wayne Gacy
Penicillin
Mick Jagger
Noam Chomsky
Hernia
Serbia
Rachel McAdams
Andy Gibb
Los Angeles Lakers
Pink (singer)
Idina Menzel
Huntington's disease
The Witch (2015 film)
Transformers: The Last Knight
Blink-182
Charles Kushner
Ronda Rousey
Casualties of the September 11 attacks
A Beautiful Mind (film)
Downton Abbey
Diane Kruger
The Walking Dead (season 7)
The Mummy (1999 film)
Will Arnett
Mario Balotelli
World Wide Web
Pokémon
It (miniseries)
Drunk History
Captain America
Miley Cyrus
Disha Patani
Ghost in the Shell (2017 film)
Trevor Noah
The Lost City of Z (film)
Territories of the United States
Memorial Day
2017 in film
Tommy Lee Jones
Empire State Building
Sepsis
Education in Japan
Elizabeth Debicki
Katey Sagal
Chelsea Peretti
Bella Thorne
Candace Cameron Bure
TIPS: To create new content for your website or blog...
  1. Enter the title of a Wikipedia article in the box above.
  2. Select your options using the checkboxes, or use default settings.
  3. Click the 'go' button to retrieve the article.
  4. Click the 'Copy Code' button to copy the source code of the article to your clipboard.
  5. Paste the source code into your favorite HTML editor.
  6. Edit the content to suit your needs.
  7. Publish your new content to your website or blog.
  8. IMPORTANT: Before publishing, be sure to make significant changes to avoid creating duplicate content.
buy this site
Custom Website Development